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Basics of Precision Engineering

Handbook of Biomarkers and Precision Medicine

Handbook of Biomarkers and Precision Medicine

The field of Biomarkers and Precision Medicine in drug development is rapidly evolving and this book presents a snapshot of exciting new approaches. By presenting a wide range of biomarker applications discussed by knowledgeable and experienced scientists readers will develop an appreciation of the scope and breadth of biomarker knowledge and find examples that will help them in their own work. Maria Freire Foundation for the National Institutes of HealthHandbook of Biomarkers and Precision Medicine provides comprehensive insights into biomarker discovery and development which has driven the new era of Precision Medicine. A wide variety of renowned experts from government academia teaching hospitals biotechnology and pharmaceutical companies share best practices examples and exciting new developments. The handbook aims to provide in-depth knowledge to research scientists students and decision makers engaged in Biomarker and Precision Medicine-centric drug development. Features:Detailed insights into biomarker discovery validation and diagnostic development with implementation strategiesLessons-learned from successful Precision Medicine case studiesA variety of exciting and emerging biomarker technologiesThe next frontiers and future challenges of biomarkers in Precision MedicineClaudio Carini Mark Fidock and Alain van Gool are internationally recognized as scientific leaders in Biomarkers and Precision Medicine. They have worked for decades in academia and pharmaceutical industry in EU USA and Asia. Currently Dr. Carini is Honorary Faculty at Kings’s College School of Medicine London UK. Dr. Fidock is Vice President of Precision Medicine Laboratories at AstraZeneca Cambridge UK. Prof. dr. van Gool is Head Translational Metabolic Laboratory at Radboud university medical school Nijmegen NL.

GBP 66.99
1

Precision Agriculture Technology for Crop Farming

Precision Agriculture Technology for Crop Farming

Explores the Sustainable Development of Agriculture in TechnologyPrecision agriculture technology when properly integrated into the crop production process can greatly improve overall production and sustainability. Precision Agriculture Technology for Crop Farming focuses on the technology of site-specific crop management; detailing applications for sensing data handling modeling and control. Written by experts who have contributed significantly to the development of precision agriculture technology this book reviews its history—establishing background on the various processes and applications—describes the current status and offers insight into the future technology of precision agriculture. Introducing processes and applications based on a global scale the book reveals how precision agriculture can be used in large-scale agriculture community agriculture and diversified farming. It includes site-specific information from a variety of information sources for planning planting growing and harvesting agricultural crops. It also presents a new concept based on the control system theory that can be used to formulate systematic methods for more effective precision crop production. In addition this author:Describes yield monitors and guidance systems GPS-based soil sampling real-time crop and soil sensors and remote sensingEvaluates a Japanese model of community-based precision agriculture aimed at high profitability and reliability under regional and environmental constraintsHighlights autonomous vehicles field robots and other intelligent machinery emerging developments and future technology in the field of production agriculturePrecision Agriculture Technology for Crop Farming provides an overview of precision agriculture technology development discusses current and future considerations and aims to facilitate the successful integration of precision agriculture technology.

GBP 44.99
1

Precision Farming Soil Fertility and Productivity Aspects

Companion Diagnostics (CDx) in Precision Medicine

Foundations of Ultra-Precision Mechanism Design

Precision Metal Additive Manufacturing

Precision Metal Additive Manufacturing

Additive manufacturing (AM) is a fast-growing sector with the ability to evoke a revolution in manufacturing due to its almost unlimited design freedom and its capability to produce personalised parts locally and with efficient material use. AM companies however still face technological challenges such as limited precision due to shrinkage built-in stresses and limited process stability and robustness. Moreover often post-processing is needed due to high roughness and remaining porosity. Qualified trained personnel are also in short supply. In recent years there have been dramatic improvements in AM design methods process control post-processing material properties and material range. However if AM is going to gain a significant market share it must be developed into a true precision manufacturing method. The production of precision parts relies on three principles: Production is robust (i. e. all sensitive parameters can be controlled). Production is predictable (for example the shrinkage that occurs is acceptable because it can be predicted and compensated in the design). Parts are measurable (as without metrology accuracy repeatability and quality assurance cannot be known). AM of metals is inherently a high-energy process with many sensitive and inter-related process parameters making it susceptible to thermal distortions defects and process drift. The complete modelling of these processes is beyond current computational power and novel methods are needed to practicably predict performance and inform design. In addition metal AM produces highly textured surfaces and complex surface features that stretch the limits of contemporary metrology. With so many factors to consider there is a significant shortage of background material on how to inject precision into AM processes. Shortage in such material is an important barrier for a wider uptake of advanced manufacturing technologies and a comprehensive book is thus needed. This book aims to inform the reader how to improve the precision of metal AM processes by tackling the three principles of robustness predictability and metrology and by developing computer-aided engineering methods that empower rather than limit AM design. Richard Leach is a professor in metrology at the University of Nottingham and heads up the Manufacturing Metrology Team. Prior to this position he was at the National Physical Laboratory from 1990 to 2014. His primary love is instrument building from concept to final installation and his current interests are the dimensional measurement of precision and additive manufactured structures. His research themes include the measurement of surface topography the development of methods for measuring 3D structures the development of methods for controlling large surfaces to high resolution in industrial applications and the traceability of X-ray computed tomography. He is a leader of several professional societies and a visiting professor at Loughborough University and the Harbin Institute of Technology. Simone Carmignato is a professor in manufacturing engineering at the University of Padua. His main research activities are in the areas of precision manufacturing dimensional metrology and industrial computed tomography. He is the author of books and hundreds of scientific papers and he is an active member of leading technical and scientific societies. He has been chairman organiser and keynote speaker for several international conferences and received national and international awards including the Taylor Medal from CIRP the International Academy for Production Engineering. | Precision Metal Additive Manufacturing

GBP 140.00
1

High-Speed Precision Motion Control

High-Speed Precision Motion Control

Edited by Takashi Yamaguchi Mitsuo Hirate and Chee Khiang Pang with contributions from pioneers known for their ground-breaking work High-Speed Precision Motion Control discusses high-precision and fast servo controls in hard disk drives (HDDs). The chapter authors describe the control technologies they’ve developed most of which have already been successfully applied to mass production of HDDs. As the proposed methodologies have been verified on commercial HDDs at the very least these advanced control technologies can also be readily applied to precision motion control of other mechatronic systems e. g. scanners micro-positioners photocopiers atomic force microscopes (AFMs) etc. Each self-contained chapter progresses from concept to technique and presents application examples in automotive aerospace aeronautical and manufacturing engineering. The control technologies are categorized into high-speed servo control precision control and environment-friendly control making it easy to find an appropriate control technology according to their domain of application. The book also makes MATLAB®/SIMULINK® codes for benchmark problems available for download. The control technologies described range from fundamental classical control theories to advanced topics such as multi-rate control. The content contains a healthy balance between materials from the contributor’s research works and that in the wider literature. The resulting resource empowers engineers and managers with the knowledge and know-how to make important decisions and policies.

GBP 74.99
1

Soil-Specific Farming Precision Agriculture

GBP 44.99
1

Dynamic Treatment Regimes Statistical Methods for Precision Medicine

Dynamic Treatment Regimes Statistical Methods for Precision Medicine

Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics data science and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules each corresponding to a key decision point in a disease or disorder process where each rule takes as input patient information and returns the treatment option he or she should receive. Thus a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime one that if used to select treatments for the patient population would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www. dtr-book. com includes updates corrections new papers and links to useful websites. | Dynamic Treatment Regimes Statistical Methods for Precision Medicine

GBP 44.99
1

Healthcare 4.0 Health Informatics and Precision Data Management

Precision Crystallization Theory and Practice of Controlling Crystal Size

Precision Crystallization Theory and Practice of Controlling Crystal Size

Despite the fact that crystals make up an estimated 80% of chemical and pharmaceutical products few resources exist that provide practical guidance on achieving precision control of their size and size distribution. Based on a model developed by the author and his colleagues Precision Crystallization: Theory and Practice of Controlling Crystal Size presents scientists and product engineers with the tools to control crystal nucleation enabling them to ultimately control crystal size and size distribution for batch and continuous crystallizations. At the cutting edge of crystallization science and technology this volume presents information never before available. Introducing the Balanced Nucleation and Growth (BNG) model the book demonstrates how the results of the nucleation process are quantitatively related to practical experimental control values such as:reaction addition ratecrystal solubilitytemperatureresidence time (continuous crystallizations)the effect of ripening agents (crystal supersizing) during nucleationthe effect of crystal growth restrainers (crystal nanosizing) during nucleationcontrol of renucleationThe author shows how the BNG theory predicts previously unknown phenomena and also how it corrects erroneous perceptions of the importance of reaction volume on the outcome of crystal nucleation. Going above and beyond classical nucleation theories which rely to a large extent on guesswork the BNG model gives precise guidance to scientists working in a range of critical areas leading to promising implications for research quality control product development production processes pilot plant operations and manufacturing. | Precision Crystallization Theory and Practice of Controlling Crystal Size

GBP 56.99
1

Colour and Light Spatial Experience

Precision Agriculture for Sustainability and Environmental Protection

Precision Agriculture for Sustainability and Environmental Protection

Precision agriculture (PA) involves the application of technologies and agronomic principles to manage spatial and temporal variation associated with all aspects of agricultural production in order to improve crop performance and environmental quality. The focus of this book is to introduce a non-specialist audience to the the role of PA in food security environmental protection and sustainable use of natural resources as well as its economic benefits. The technologies covered include yield monitors and remote sensing and the key agronomic principles addressed are the optimal delivery of fertilizers water and pesticides to crops only when and where these are required. As a result it is shown that both food production and resource efficiency can be maximized without waste or damage to the environment such as can occur from excessive fertilizer or pesticide applications. The authors of necessity describe some technicalities about PA but the overall aim is to introduce readers who are unfamiliar with PA to this very broad subject and to demonstrate the potential impact of PA on the environment and economy. The book shows how farmers can place sustainability of the environment at the centre of their operations and that this is improved with the application of PA. The range of topics described includes sampling and mapping weed and pest control proximal and remote sensing spatio-temporal analysis for improving management management zones and water management. These are illustrated with case studies on sampling and mapping biofuels from sugar cane and maize paddy rice cultivation and cotton production. Chapter 3 of this book is freely available as a downloadable Open Access PDF at http://www. tandfebooks. com/page/openaccess It has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 3. 0 license. | Precision Agriculture for Sustainability and Environmental Protection

GBP 39.99
1

US Counterterrorism and the Human Rights of Foreigners Abroad Putting the Gloves Back On?

US Counterterrorism and the Human Rights of Foreigners Abroad Putting the Gloves Back On?

This book examines why the United States has introduced safeguards that are designed to prevent their counterterrorism policies from causing harm to non-US citizens beyond US territory. It investigates what made US policymakers take steps to put the gloves back on through five case studies on the emergence of such safeguards related to the right not to be tortured the right not to be arbitrarily detained the right to life (in connection with targeted killing operations) the right to seek asylum (in connection with refugee resettlement) and the right to privacy (in connection with foreign mass surveillance). The book exposes two mechanisms – coercion and strategic learning – which explain why the United States has introduced what the authors refer to as extraterritorial human rights safeguards thus demonstrating that the emerging norm that states have human rights obligations towards foreigners beyond their borders constrains policy choices. This book will be of key interest to scholars and students of human rights counterterrorism US foreign policy human rights law and more broadly to political science and international relations. The Open Access version of this book available at: http://www. taylorfrancis. com has been made available under a Creative Commons Attribution-Non Commercial-No Derivatives 4. 0 license. | US Counterterrorism and the Human Rights of Foreigners Abroad Putting the Gloves Back On?

GBP 130.00
1

Handbook of Measurements Benchmarks for Systems Accuracy and Precision

Handbook of Measurements Benchmarks for Systems Accuracy and Precision

Planning measuring and paying attention to details form the basis for all successful engineering operations. Measurements pervade everything we do and must be viewed from a systems perspective. A comprehensive all-encompassing guide to measurements Handbook of Measurements: Benchmarks for Systems Accuracy and Precision focuses on high-level engineering computations essential for benchmarks and technical innovation. The book uses a systems framework and a technically rigorous approach to systems linking of measurements—an approach that sets it apart from other handbooks. The popular saying measure twice and cut once bears out the importance of measurements in human endeavors. This handbook covers both qualitative and quantitative topics of measurement. It opens with a chapter on the fundamentals of measurement and includes coverage of human-centric measurements such as measurement of personnel productivity and contractor performance. It concludes with three appendices on measurement references conversion factors equations formulas and statistics for measurement. It is well understood that humans cannot manage anything that cannot be measured. All elements involved in our day-to-day decision making involve some form of measurement whether in the kitchen retail sports service operations geographical exploration health care delivery worker productivity clothing design engineering product design or space craft launching. Measuring an attribute of a system and then analyzing it against some standard some specification some best practice or some benchmark empower a decision maker to take appropriate and timely actions. This book gives you a guide for sustainable practices to ensure accurate measurements helping you make decisions backed by metrics. | Handbook of Measurements Benchmarks for Systems Accuracy and Precision

GBP 56.99
1

Seed Inoculation Coating and Precision Pelleting Science Technology and Practical Applications

Ultraviolet Light in Food Technology Principles and Applications

Remote Sensing of Night-time Light

Remote Sensing of Night-time Light

Satellite images acquired at night provide a visually arresting perspective of the Earth and the human activities that light up the otherwise mostly dark Earth. These night-time light satellite images can be compiled into a geospatial time series that represent an invaluable source of information for both the natural and social sciences. Night-time light remote sensing has been shown to be particularly useful for a range of natural science and social science applications including studies relating to urban development demography sociology fishing activity light pollution and the consequences of civil war. Key sensors for these time-series include the Defense Meteorological Satellite Program’s Operational Linescan System (DMSP/OLS) and the Suomi National Polar-orbiting Partnership Satellite’s Visible Infrared Imaging Radiometer Suite Day/Night Band (Suomi NPP/VIIRS DNB). An increasing number of alternative sources are also available including high spatial resolution and multispectral sensors. This book captures key methodological issues associated with pre-processing night-time light data documents state of the art analysis methods and explores a wide range of applications. Major sections focus on NPP/VIIRS DNB processing; inter-calibration between NPP/VIIRS and DMPS/OLS; applications associated with socio-economic activities applications in monitoring urbanization; and fishing activity monitoring. The chapters in this book were originally published as a special issue of the International Journal of Remote Sensing. | Remote Sensing of Night-time Light

GBP 38.99
1

Designing with Light An Introduction to Stage Lighting

Beautiful Light An Insider’s Guide to LED Lighting in Homes and Gardens

Theory of Nonclassical States of Light

Organic Light-Emitting Materials and Devices

Organic Light-Emitting Materials and Devices

Organic Light-Emitting Materials and Devices provides a single source of information covering all aspects of OLEDs including the systematic investigation of organic light-emitting materials device physics and engineering and manufacturing and performance measurement techniques. This Second Edition is a compilation of the advances made in recent years and of the challenges facing the future development of OLED technology. Featuring chapters authored by internationally recognized academic and industrial experts this authoritative text: Introduces the history fundamental physics and potential applications of OLEDs Reviews the synthesis properties and device performance of electroluminescent materials used in OLEDs Reflects the current state of molecular design exemplifying more than 600 light-emitting polymers and highlighting the most efficient materials and devices Explores small molecules-based OLEDs detailing hole- and electron-injection and electron-transport materials electron- and hole-blocking materials sensitizers and fluorescent and phosphorescent light-emitting materials Describes solution-processable phosphorescent polymer LEDs energy transfer processes polarized OLEDs anode materials and vapor deposition manufacturing techniques employed in OLED fabrication Discusses flexible display the backplane circuit technology for organic light-emitting displays and the latest microstructural characterization and performance measurement techniques Contains abundant diagrams device configurations and molecular structures clearly illutrating the presented ideas Organic Light-Emitting Materials and Devices Second Edition offers a comprehensive overview of the OLED field and can serve as a primary reference for those needing additional information in any particular subarea of organic electroluminescence. This book should attract the attention of materials scientists synthetic chemists solid-state physicists and electronic device engineers as well as industrial managers and patent lawyers engaged in OLED-related business areas.

GBP 74.99
1

Night Photography and Light Painting Finding Your Way in the Dark