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Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

Cellular Signal Processing offers a unifying view of cell signaling based on the concept that protein interactions act as sophisticated data processing networks that govern intracellular and extracellular communication. It is intended for use in signal transduction courses for undergraduate and graduate students working in biology biochemistry bioinformatics and pharmacology as well as medical students. The text is organized by three key topics central to signal transduction: the protein network its energy supply and its evolution. It covers all important aspects of cell signaling ranging from prokaryotic signal transduction to neuronal signaling and also highlights the clinical aspects of cell signaling in health and disease. This new edition includes expanded coverage of prokaryotes as well as content on new developments in systems biology epigenetics redox signaling and small non-coding RNA signaling. | Cellular Signal Processing An Introduction to the Molecular Mechanisms of Signal Transduction

GBP 66.99
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A First Course in Systems Biology

A First Course in Systems Biology

A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks understanding the modern literature and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design limit cycles and chaos parameter estimation in Excel model representations of gene regulation through transcription factors derivation of the Michaelis-Menten rate law from the original conceptual model different types of inhibition hysteresis a model of differentiation system adaptation to persistent signals nonlinear nullclines PBPK models and elementary modes. The format is a combination of instructional text and references to primary literature complemented by sets of small-scale exercises that enable hands-on experience and large-scale often open-ended questions for further reflection.

GBP 82.99
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