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Case Studies in Veterinary Immunology

Case Studies in Veterinary Immunology

Case Studies in Veterinary Immunology presents basic immunological concepts in the context of actual cases seen in clinics. It is intended for veterinary medicine students interns residents and veterinarians and serves as a valuable supplement and companion to a variety of core immunology textbooks and courses. The book includes cases describing primary immune system defects secondary immune system defects and hypersensitivity and autoimmune disorders as well as dysproteinemias and lymphoid neoplasia. Drawing on the successful approach of Geha’s Case Studies in Immunology each representative case is preceded by a discussion of the principles underlying that specific immunological mechanism. The case itself includes the presenting complaint (signalment) physical examination findings pertinent diagnostic laboratory data diagnosis and treatment options. In those instances in which a specific disorder occurs in both animals and humans the differences and similarities in the immunological mechanisms and manifestations of the disease are explored. End of case questions highlight important concepts and serve as a review aid for students. Details on standard vaccines and vaccination schedules as well as descriptions of the types of assays used for evaluation of the immune system are included as appendices.

GBP 42.99
1

Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology Structure and Dynamics of Genomes and Proteomes

Molecular Biology: Structure and Dynamics of Genomes and Proteomes second edition illustrates the essential principles behind the transmission and expression of genetic information at the level of DNA RNA and proteins. Emphasis is on the experimental basis of discovery and the most recent advances in the field while presenting a rigorous yet still concise summary of the structural mechanisms of molecular biology. Topics new to this edition include the CRISPR-Cas gene editing system Coronaviruses – structure genome vaccine and drug development and newly recognized mechanisms for transcription termination. The text is written for advanced undergraduate or graduate-level courses in molecular biology. Key Features Highlights the experimental basis of important discoveries in molecular biology Thoroughly updated with new information on gene editing tools viruses and transcription mechanisms termination and antisense Provides learning objectives for each chapter Includes a list of relevant videos from the Internet about the topics covered in the chapter | Molecular Biology Structure and Dynamics of Genomes and Proteomes

GBP 64.99
1

A First Course in Systems Biology

A First Course in Systems Biology

A First Course in Systems Biology is an introduction for advanced undergraduate and graduate students to the growing field of systems biology. Its main focus is the development of computational models and their applications to diverse biological systems. The book begins with the fundamentals of modeling then reviews features of the molecular inventories that bring biological systems to life and discusses case studies that represent some of the frontiers in systems biology and synthetic biology. In this way it provides the reader with a comprehensive background and access to methods for executing standard systems biology tasks understanding the modern literature and launching into specialized courses or projects that address biological questions using theoretical and computational means. New topics in this edition include: default modules for model design limit cycles and chaos parameter estimation in Excel model representations of gene regulation through transcription factors derivation of the Michaelis-Menten rate law from the original conceptual model different types of inhibition hysteresis a model of differentiation system adaptation to persistent signals nonlinear nullclines PBPK models and elementary modes. The format is a combination of instructional text and references to primary literature complemented by sets of small-scale exercises that enable hands-on experience and large-scale often open-ended questions for further reflection.

GBP 82.99
1

Molecular and Cellular Biology of Viruses

Molecular and Cellular Biology of Viruses

Viruses interact with host cells in ways that uniquely reveal a great deal about general aspects of molecular and cellular structure and function. Molecular and Cellular Biology of Viruses leads students on an exploration of viruses by supporting engaging and interactive learning. All the major classes of viruses are covered with separate chapters for their replication and expression strategies and chapters for mechanisms such as attachment that are independent of the virus genome type. Specific cases drawn from primary literature foster student engagement. End-of-chapter questions focus on analysis and interpretation with answers being given at the back of the book. Examples come from the most-studied and medically important viruses such as HIV influenza and poliovirus. Plant viruses and bacteriophages are also included. There are chapters on the overall effect of viral infection on the host cell. Coverage of the immune system is focused on the interplay between host defenses and viruses with a separate chapter on medical applications such as anti-viral drugs and vaccine development. The final chapter is on virus diversity and evolution incorporating contemporary insights from metagenomic research. Key selling feature: Readable but rigorous coverage of the molecular and cellular biology of viruses Molecular mechanisms of all major groups including plant viruses and bacteriophages illustrated by example Host-pathogen interactions at the cellular and molecular level emphasized throughout Medical implications and consequences included Quality illustrations available to instructors Extensive questions and answers for each chapter

GBP 69.99
1

Biology for the Health Sciences Mechanisms of Disease

Biology for the Health Sciences Mechanisms of Disease

Biology is central to our understanding of health and disease and to the development of effective treatments and thus it is critical that health professionals have a solid grounding and knowledge comfort in the pathogenesis and mechanisms of disease processes. This innovative new textbook draws these topics together providing an accessible introduction across four central disciplines - basic biology biotechnology non-infectious disease and infectious disease. Key Features: Provides students of biology and those going into health care professions with a strong foundation to understand the pathogenesis of disease at the molecular and cellular level Focuses on the etiology and pathophysiology of the major human diseases by body system including diabetes and nutritional disorders cardiovascular disease neurodegenerative diseases and cancer aligned to medicine and health science course structure Covers mechanisms of infectious disease transmission as well as disease pathophysiology and considers the impact of antibiotic resistance Reviews the applications of biotechnology and genomics to human health in diagnosis and treatment as well as to our understanding of disease and disease surveillance Each chapter contains a mini glossary of key terms and associated definitions and review questions allow students to assess how much of the chapter they have understood Digital resources accompany the textbook such as interactive quizzes for students to engage with and figure slides of the book's illustrations that instructors can use in lectures Enhanced throughout with plentiful illustrations Biology for the Health Sciences is an essential companion for any student of the health sciences and for biological science students studying the causes of disease as part of a wider course. | Biology for the Health Sciences Mechanisms of Disease

GBP 49.99
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