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Personalizing Precision Medicine - Kristin Ciriello Pothier - Bog - John Wiley & Sons Inc - Plusbog.dk

Precision Medicine, AI and the Science of Personalized Healthcare - James Wallace - Bog - John Wiley & Sons Inc - Plusbog.dk

Precision Medicine, AI and the Science of Personalized Healthcare - James Wallace - Bog - John Wiley & Sons Inc - Plusbog.dk

A fascinating combination of patient stories and scientific explanation shedding light on the most promising trend in healthcare today: precision medicine In Precision Medicine, AI and the Science of Personalized Healthcare, senior researcher at Harvard Business School and former CEO of DecisionRx, a pioneering medication therapy optimization company, James Wallace, delivers an eye-opening new discussion of how cutting-edge precision medicine is transforming the cost, access, and outcomes of modern healthcare. The author relies on real-world experiences that showcase the practical, human benefits of precision medicine and how those benefits can accrue to people from all walks of life. You'll discover how personalized treatments—those based on a patient's genetic, environmental, and lifestyle attributes—can do more than traditional medicine to combat a wide variety of genetic disorders, chronic illnesses, and treatment inefficiencies. You'll also learn about precision medicine's potential to lower healthcare costs for everyone while improving outcomes. Inside the book: Explorations of how precision medicine can address the triple crisis of cost, access, and quality that currently plagues the US healthcare systemUnique combinations of compelling human stories and accessible scientific explanations that render a complex subject approachable and relatableA compelling argument for how the precision medicine movement can transform the healthcare system and the lives of the people who navigate it every day Perfect for healthcare, technology, and business professionals grappling with the skyrocketing costs of patient care, Precision Medicine, AI and the Science of Personalized Healthcare is also a must-read for healthcare consumers frustrated by the current, “one-size-fits-all” approach to medicine.

DKK 300.00
1

Precision Agriculture in the 21st Century - National Research Council - Bog - National Academies Press - Plusbog.dk

Precision Agriculture in the 21st Century - National Research Council - Bog - National Academies Press - Plusbog.dk

Sensors, satellite photography, and multispectral imaging are associated with futuristic space and communications science. Increasingly, however, they are considered part of the future of agriculture. The use of advanced technologies for crop production is known as precision agriculture, and its rapid emergence means the potential for revolutionary change throughout the agricultural sector. Precision Agriculture in the 21st Century provides an overview of the specific technologies and practices under the umbrella of precision agriculture, exploring the full implications of their adoption by farmers and agricultural managers. The volume discusses how precision agriculture could dramatically affect decisionmaking in irrigation, crop selection, pest management, environmental issues, and pricing and market conditions. It also examines the geographical dimensions—farm, regional, national—of precision agriculture and looks at how quickly and how widely the agricultural community can be expected to adopt the new information technologies. Precision Agriculture in the 21st Century highlights both the uncertainties and the exciting possibilities of this emerging approach to farming. This book will be important to anyone concerned about the future of agriculture: policymakers, regulators, scientists, farmers, educators, students, and suppliers to the agricultural industry. Table of ContentsFront MatterExecutive Summary1 Dimensions of Precision Agriculture2 A New Way to Practice Agriculture3 Adoption of Precision Agriculture4 Public Policy and Precision AgricultureReferencesGlossaryAuthorsIndex

DKK 338.00
1

Precision Oncology and Cancer Biomarkers - - Bog - Springer Nature Switzerland AG - Plusbog.dk

Precision Oncology and Cancer Biomarkers - - Bog - Springer Nature Switzerland AG - Plusbog.dk

Introduction (Anne Bremer and Roger Strand).- Chapter 1. Precision oncology in the news (Mille Stenmarck and Irmelin Nilsen).- Chapter 2. Cancer biomarkers from a patient''s perspective (Karen Gissum).- Chapter 3. Breast cancer: reconstruction of trouble (Hanna Dillekås).- Chapter 4. HER2: an apparently ''simple'' biomarkers revealing the complexities and uncertainties of precision oncology (Elisabeth Wik, Anne Bremer and Lars A. Akslen).- Chapter 5. Integrating genomic and non-genomic factors in shaping the personal fingerprint in personalised cancer treatments (Mariano Bizzari and Andrea Pensotti).- Chapter 6. Systems medicine and perspectives on precision oncology (Rune Kleppe, Inge Jonassen and Roger Strand).- Chapter 7. Precision oncology: the challenges related to publishing (Maria Lie Lotsberg).- Chapter 8. Filled with Desire, Perceive Molecules (Caroline Engen and Roger Strand).- Chapter 9. Precision health and ethical ambiguity: How much cancer can we afford to prevent? (Leonard Fleck).- Chapter 10. New cancer drugs and the public controversy: how can biomarkers contribute? (Eirik Tranvåg and Roger Strand).- Chapter 11. Assessing the cost-effectiveness of targeted therapies and checkpoint inhibitors (John Cairns).- Chapter 12. Real-world data in Health Technology Assessment of targeted cancer therapy (Jiyeon Kang).- Chapter 13. Negotiating safety and resources in a first in human cancer trial in Denmark (Line Hillersdal).- Conclusion: Precision oncology: Fact or fantasy? (Roger Strand and Anne Bremer).

DKK 349.00
1

Precision Marketing - Jeff Zabin - Bog - John Wiley & Sons Inc - Plusbog.dk

A Knitters Guide to Gloves - Angharad Thomas - Bog - The Crowood Press Ltd - Plusbog.dk

Fantasies of Precision - Ashley Lazevnick - Bog - University of Minnesota Press - Plusbog.dk

Fantasies of Precision - Ashley Lazevnick - Bog - University of Minnesota Press - Plusbog.dk

Redefining the artistic movement that helped shape American modernism In the early decades of the twentieth century, a loose contingent of artists working in and around New York City gave rise to the aesthetic movement known as precisionism, primarily remembered for its exacting depictions of skyscrapers, factories, machine parts, and other symbols of a burgeoning modernity. Although often regarded as a singular group, these artists were remarkably varied in their subject matter and stylistic traits. Fantasies of Precision excavates the surprising ties that connected them, exploring notions of precision across philosophy, technology, medicine, and many other fields. Bookended by discussions of the landmark First Biennial Exhibition of Painting at the Whitney Museum in 1932, this study weaves together a series of interconnected chapters illuminating the careers of Charles Sheeler, Georgia O’Keeffe, and Charles Demuth. Built on a theoretical framework of the writing of modernist poets Marianne Moore and William Carlos Williams, Fantasies of Precision outlines an “ethos of precision” that runs through the diverse practices of these artists, articulating how the broad range of enigmatic imagery they produced was underpinned by shared strategies of restraint, humility, and slowness. Questioning straightforward modes of art historical classification, Ashley Lazevnick redefines the concept that designated the precisionist movement. Through its cross-disciplinary approach and unique blend of historiography and fantasy, Fantasies of Precision offers a comprehensive reevaluation of one of the defining movements of artistic modernism.

DKK 295.00
1

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine - Institute For Laboratory Animal Research - Bog - National

Advancing Disease Modeling in Animal-Based Research in Support of Precision Medicine - Institute For Laboratory Animal Research - Bog - National

Precision medicine is focused on the individual and will require the rapid and accurate identification and prioritization of causative factors of disease. To move forward and accelerate the delivery of the anticipated benefits of precision medicine, developing predictable, reproducible, and reliable animal models will be essential. In order to explore the topic of animal-based research and its relevance to precision medicine, the National Academies of Sciences, Engineering, and Medicine convened a 2-day workshop on October 5 and 6, 2017. The workshop was designed to focus on the development, implementation, and interpretation of model organisms to advance and accelerate the field of precision medicine. Participants examined the extent to which next-generation animal models, designed using patient data and phenotyping platforms targeted to reveal and inform disease mechanisms, will be essential to the successful implementation of precision medicine. This publication summarizes the presentations and discussions from the workshop. Table of ContentsFront Matter1 Introduction to Precision Medicine and Animal Models2 Existing Precision Medicine Initiatives3 The Promise and Perils of Animal Models4 Reproducibility and Predictivity5 In Vitro Alternatives to Animal Models6 Assessing Safety and Toxicology7 Patient Perspectives8 Reflections on the WorkshopReferencesAppendix A: AgendaAppendix B: Planning Committee BiographiesAppendix C: Speaker Biographies

DKK 344.00
1

Enabling Precision Medicine - Health And Medicine Division - Bog - National Academies Press - Plusbog.dk

Enabling Precision Medicine - Health And Medicine Division - Bog - National Academies Press - Plusbog.dk

Those involved in the drug development process face challenges of efficiency and overall sustainability due in part to high research costs, lengthy development timelines, and late-stage drug failures. Novel clinical trial designs that enroll participants based on their genetics represent a potentially disruptive change that could improve patient outcomes, reduce costs associated with drug development, and further realize the goals of precision medicine. On March 8, 2017, the Forum on Drug Discovery, Development, and Translation and the Roundtable on Genomics and Precision Health of the National Academies of Sciences, Engineering, and Medicine hosted the workshop Enabling Precision Medicine: The Role of Genetics in Clinical Drug Development. Participants examined successes, challenges, and possible best practices for effectively using genetic information in the design and implementation of clinical trials to support the development of precision medicines, including exploring the potential advantages and disadvantages of such trials across a variety of disease areas. This publication summarizes the presentations and discussions from the workshop. Table of ContentsFront Matter1 Introduction2 Overarching Considerations for Implementing Successful Genetics-Enabled Drug Development3 Case Studies in Precision Drug Development4 Integrating Genetics into the Drug Development Pathway for Complex Diseases5 Finding Innovative Ways to Integrate Genetic Research into the Drug Development Process6 Reflecting Back and Looking Forward: Key Themes and Potential Next Steps in Genetics-Enabled Drug DevelopmentAppendix A: ReferencesAppendix B: Statement of Task and Workshop AgendaAppendix C: Speaker Biographical SketchesAppendix D: Registered Attendees

DKK 370.00
1

Challenges and Opportunities for Precision and Personalized Nutrition - Health And Medicine Division - Bog - National Academies Press - Plusbog.dk

The Ethics of Precision Medicine - Paul Scherz - Bog - University of Notre Dame Press - Plusbog.dk

The Ethics of Precision Medicine - Paul Scherz - Bog - University of Notre Dame Press - Plusbog.dk

Paul Scherz explores the ethical challenges raised by precision medicine and its focus on medical risk as opposed to current disease. Genetic technologies and artificial intelligence are rapidly changing the landscape of medical practice and patient care. In the emerging field of precision medicine, a patient's risk factors—especially genetic risk factors—are incorporated into an all-encompassing plan to prevent future disease. But identifying at-risk individuals through technologies such as wearable devices and direct-to-consumer genetic sequencing can undermine the overall experience of health. The potential for overdiagnosis and overtreatment grows as patients are prescribed medications and receive prophylactic surgeries that carry inherent risks. Also, as the medical industry shifts its attention from individuals to trends in the general population, the one-to-one practitioner-patient relationship becomes strained. Using the lens of virtue ethics and theological bioethics, The Ethics of Precision Medicine offers suggestions for better implementing precision medicine to treat those currently suffering from or at high risk of disease, while also recognizing that effectively preventing disease depends, ultimately, on addressing the social determinants of health. The book provides a new perspective on the problems of contemporary healthcare, proposing practical steps that individuals and institutions can take to ensure that the advanced technologies of precision medicine can be used to promote human flourishing.

DKK 338.00
1