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Precision Haematological Cancer Medicine - Tariq I. Mughal - Bog - Taylor & Francis Inc - Plusbog.dk

Quantitative Methods for Precision Medicine - Rongling Wu - Bog - Taylor & Francis Inc - Plusbog.dk

Quantitative Methods for Precision Medicine - Rongling Wu - Bog - Taylor & Francis Inc - Plusbog.dk

Modern medicine is undergoing a paradigm shift from a "one-size-fits-all" strategy to a more precise patient-customized therapy and medication plan. While the success of precision medicine relies on the level of pharmacogenomic knowledge, dissecting the genetic mechanisms of drug response in a sufficient detail requires powerful computational tools. Quantitative Methods for Precision Medicine: Pharmacogenomics in Action presents the advanced statistical methods for mapping pharmacogenetic control by integrating pharmacokinetic and pharmacodynamic principles of drug-body interactions. Beyond traditional reductionist-based statistical genetic approaches, statistical formulization in this book synthesizes elements of multiple disciplines to infer, visualize, and track how pharmacogenes interact together as an intricate but well-coordinated system to mediate patient-specific drug response. Features: - Functional and systems mapping models to characterize the genetic architecture of multiple medication processes - Statistical methods for analyzing informative missing data in pharmacogenetic association studies - Functional graph theory of inferring genetic interaction networks from association data - Leveraging the concept of epistasis to capture its bidirectional, signed and weighted properties - Modeling gene-induced cell-cell crosstalk and its impact on drug response - A graph model of drug-drug interactions in combination therapies - Critical methodological issues to improve pharmacogenomic research as the cornerstone of precision medicine This book is suitable for graduate students and researchers in the fields of biology, medicine, bioinformatics and drug design and delivery who are interested in statistical and computational modelling of biological processes and systems. It may also serve as a major reference for applied mathematicians, computer scientists, and statisticians who attempt to develop algorithmic tools for genetic mapping, systems pharmacogenomics and systems biology. It can be used as both a textbook and research reference. Professionals in pharmaceutical sectors who design drugs and clinical doctors who deliver drugs will also find it useful.

DKK 902.00
1

Precision Photoshop - Lopsie Schwartz - Bog - Taylor & Francis Inc - Plusbog.dk

Precision Photoshop - Lopsie Schwartz - Bog - Taylor & Francis Inc - Plusbog.dk

The Essentials of Photoshop for Creative Professionals There are plenty of books on Photoshop for photographers; for everyone else, there’s Precision Photoshop: Creating Powerful Visual Effects . In clear, conversational language using extensive images and screenshots, this book gives you in-depth guidance on learning how to use Photoshop. The author shares her practical knowledge and insider tips gleaned from years working on visual effects in the entertainment business. Requiring no prior experience, the book first offers a step-by-step beginner’s tutorial on the main features of Photoshop, with the tutorial files available on the book’s CRC Press web page. It next shows you how to manage various assets, such as text, 3D, or HDRI files, and provides solutions to the most common questions asked by new Photoshop users. The author explains how to work with camera raw files and describes how to unlock your artistic potential through Photoshop’s powerful tools. She also covers more advanced tutorials involving higher concepts and specific source images, such as creating panoramas, high-contrast images, 3D effects, and motion. Illustrating key techniques with examples of production-quality work, this book delves deep into aspects most important to creative professionals. Whether you’re a beginner or more experienced user, you will find precise instruction on critical elements of the workflow.

DKK 597.00
1

Light and Surface - Denis Kozlov - Bog - Taylor & Francis Inc - Plusbog.dk

Reel Arguments - Andrew Light - Bog - Taylor & Francis Inc - Plusbog.dk

Alternate Light Source Imaging - Jeffrey Buszka - Bog - Taylor & Francis Inc - Plusbog.dk

Reevaluating Evaluation - - Bog - Taylor & Francis Inc - Plusbog.dk

Seed Inoculation, Coating and Precision Pelleting - John Lloyd - Bog - Taylor & Francis Inc - Plusbog.dk

Not Light, but Fire - Matthew R. Kay - Bog - Taylor & Francis Inc - Plusbog.dk

Dynamic Treatment Regimes - Shannon T. Holloway - Bog - Taylor & Francis Inc - Plusbog.dk

Dynamic Treatment Regimes - Shannon T. Holloway - Bog - Taylor & Francis Inc - Plusbog.dk

Dynamic Treatment Regimes: Statistical Methods for Precision Medicine provides a comprehensive introduction to statistical methodology for the evaluation and discovery of dynamic treatment regimes from data. Researchers and graduate students in statistics, data science, and related quantitative disciplines with a background in probability and statistical inference and popular statistical modeling techniques will be prepared for further study of this rapidly evolving field. A dynamic treatment regime is a set of sequential decision rules, each corresponding to a key decision point in a disease or disorder process, where each rule takes as input patient information and returns the treatment option he or she should receive. Thus, a treatment regime formalizes how a clinician synthesizes patient information and selects treatments in practice. Treatment regimes are of obvious relevance to precision medicine, which involves tailoring treatment selection to patient characteristics in an evidence-based way. Of critical importance to precision medicine is estimation of an optimal treatment regime, one that, if used to select treatments for the patient population, would lead to the most beneficial outcome on average. Key methods for estimation of an optimal treatment regime from data are motivated and described in detail. A dedicated companion website presents full accounts of application of the methods using a comprehensive R package developed by the authors. The authors’ website www.dtr-book.com includes updates, corrections, new papers, and links to useful websites.

DKK 884.00
1

Professors Are from Mars , Students Are from Snickers - Ronald A. Berk - Bog - Taylor & Francis Inc - Plusbog.dk

Photosynthesis - V S R Das - Bog - Taylor & Francis Inc - Plusbog.dk

Biochemical Evolution - Athel Cornish Bowden - Bog - Taylor & Francis Inc - Plusbog.dk

Quantum Optomechanics - Gerard James Milburn - Bog - Taylor & Francis Inc - Plusbog.dk

Quantum Optomechanics - Gerard James Milburn - Bog - Taylor & Francis Inc - Plusbog.dk

Written by leading experimentalist Warwick P. Bowen and prominent theoretician Gerard J. Milburn, Quantum Optomechanics discusses modern developments in this novel field from experimental and theoretical standpoints. The authors share their insight on a range of important topics, including optomechanical cooling and entanglement; quantum limits on measurement precision and how to overcome them via back-action evading measurements; feedback control; single photon and nonlinear optomechanics; optomechanical synchronization; coupling of optomechanical systems to microwave circuits and two-level systems, such as atoms and superconducting qubits; and optomechanical tests of gravitational decoherence. The book first introduces the basic physics of quantum harmonic oscillators and their interactions with their environment. It next discusses the radiation pressure interaction between light and matter, deriving common Hamiltonians used in quantum optomechanics. It then focuses on the linearized regime of quantum optomechanics before exploring scenarios where the simple linearized picture of quantum optomechanics no longer holds. The authors move on to hybrid optomechanical systems in which the canonical quantum optomechanical system is coupled to another quantum object. They explain how an alternative form of a hybrid optomechanical system leads to the phenomenon of synchronization. They also consider the impact of quantum optomechanics on tests of gravitational physics.

DKK 995.00
1

Attraction and Hostility - - Bog - Taylor & Francis Inc - Plusbog.dk

Human Factors in Lighting - Peter Robert (canterbury Boyce - Bog - Taylor & Francis Inc - Plusbog.dk

Human Factors in Lighting - Peter Robert (canterbury Boyce - Bog - Taylor & Francis Inc - Plusbog.dk

The availability of electric lighting has changed the lives of people the world over, yet as a major user of electricity it has come under increasing scrutiny in recent years. This scrutiny has focused largely on the environmental consequences, with little consideration of the benefits of lighting. Human Factors in Lighting, Third Edition restores some balance to the discussion by examining the ways in which people interact with lighting. These interactions influence the ability to perform visual tasks; the perception of people, objects, and spaces; human comfort and behavior; as well as human health and safety. It is only by understanding how to use light to achieve these ends that lighting can be provided effectively and efficiently to the benefit of all. See What’s New in the Third Edition: New chapters on the non-image-forming system, lighting for pedestrians, light pollution, and lighting and electricity use Revision of all other chapters to update them to take into account the advances that have been made in our understanding of the effects of light on people over the last decade Integration of the combined effects of light via the visual and non-image-forming systems on performance and perception The book covers both the visual and the non-visual effects of light on people as well as the benefits of lighting and the costs it imposes on the environment. It details the consequences of exposure to lighting or lighting technology and the role of exposure to light on such basic functions of the body as circadian rhythms. The author combines information from many different sources and integrates them into a coherent overview of lighting practice that can be used to develop better lighting solutions at a lower environmental cost.

DKK 791.00
1

Creative Leadership Mining the Gold in Your Work Force - A. S. Migs Damiani - Bog - Taylor & Francis Inc - Plusbog.dk

Social Rules - David Braybrooke - Bog - Taylor & Francis Inc - Plusbog.dk

Attitude Structure and Function - - Bog - Taylor & Francis Inc - Plusbog.dk

Realistic Image Synthesis Using Photon Mapping - Henrik Wann Jensen - Bog - Taylor & Francis Inc - Plusbog.dk

Realistic Image Synthesis Using Photon Mapping - Henrik Wann Jensen - Bog - Taylor & Francis Inc - Plusbog.dk